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Chronic kidney disease

Proteinuria as a predictor of rapid eGFR decline

A new study by Turin et al. reports that proteinuria of increasing severity is associated with a faster rate of decline in estimated glomerular filtration rate (eGFR), regardless of eGFR at baseline. These findings support the use of proteinuria testing to identify individuals at risk of chronic kidney disease progression.

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Acknowledgements

The author's work is supported, in part, by Health and Labour Sciences Research Grants for “Research on the positioning of chronic kidney disease (CKD) in Specific Health Check and Guidance in Japan” (20230601), a grant for strategic outcome study project for renal disease (H19-renal disease-senryaku-001), the Ministry of Health, Labour and Welfare of Japan.

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Iseki, K. Proteinuria as a predictor of rapid eGFR decline. Nat Rev Nephrol 9, 570–571 (2013). https://doi.org/10.1038/nrneph.2013.177

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