Although anemia is a well-known risk factor for the development of cardiovascular disease in patients with chronic kidney disease, a number of prospective clinical trials have shown that treatment of anemia does not improve cardiovascular outcomes. The primary findings of TREAT, the largest trial to date investigating anemia treatment in patients with chronic kidney disease, have been eagerly awaited.
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The author declares associations with the following companies: Affymax (consultant, grant/research support); Amgen (consultant, honoraria, grant/research support); FibroGen (grant/research support); Hospira (consultant, honoraria, grant/research support); Janssen-Cilag (consultant, honoraria, grant/research support); Roche (consultant, honoraria, grant/research support).
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Wiecek, A. To TREAT or not to TREAT—that is the question. Nat Rev Nephrol 6, 254–255 (2010). https://doi.org/10.1038/nrneph.2010.35
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DOI: https://doi.org/10.1038/nrneph.2010.35