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Dialysis

Some patients may benefit from using high-flux membranes

Nature Reviews Nephrology volume 5, pages 434–436 (2009)Cite this article

Mortality rates of patients with low levels of serum albumin, a marker of malnutrition and inflammation, are lower when hemodialysis is performed with high-flux membranes than with low-flux membranes.

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References

  1. Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States United States Renal Data System, Annual Data Report [online], (2008).

  2. Eknoyan, G. et al. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N. Engl. J. Med. 347, 2010–2019 (2002).

    Article  Google Scholar 

  3. Cheung, A. K. et al. Effects of high-flux hemodialysis on clinical outcomes: results of the HEMO study. J. Am. Soc. Nephrol. 14, 3251–3263 (2003).

    Article  Google Scholar 

  4. Locatelli, F. et al. Effect of membrane permeability on survival of hemodialysis patients. J. Am. Soc. Nephrol. 20, 645–654 (2009).

    Article  Google Scholar 

  5. Upadhyay, A., Sosa, M. A. & Jaber, B. L. Single-use versus reusable dialyzers: the known unknowns. Clin. J. Am. Soc. Nephrol. 2, 1079–1086 (2007).

    Article  Google Scholar 

  6. Goodkin, D. A. et al. Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS). J. Am. Soc. Nephrol. 14, 3270–3277 (2003).

    Article  Google Scholar 

  7. Yoshino, M. et al. International differences in dialysis mortality reflect background general population atherosclerotic cardiovascular mortality. J. Am. Soc. Nephrol. 17, 3510–3519 (2006).

    Article  Google Scholar 

  8. Hemodialysis Adequacy 2006 Work Group. Clinical practice guidelines for hemodialysis adequacy, update 2006. Am. J. Kidney Dis. 48 (Suppl. 1), S2–S90 (2006).

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Author information

Authors and Affiliations

  1. Department of Medicine, Division of Nephrology, Kidney & Dialysis Research Laboratory, St. Elizabeth's Medical Center, Boston, MA, USA

    Victor F. Seabra, Jacob J. Clarenbach & Bertrand L. Jaber

Authors
  1. Victor F. Seabra
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  2. Jacob J. Clarenbach
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  3. Bertrand L. Jaber
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Corresponding author

Correspondence to Bertrand L. Jaber.

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Competing interests

B. L. Jaber declares association with NxStage Medical as consultant. The other authors declare no competing interests.

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Seabra, V., Clarenbach, J. & Jaber, B. Some patients may benefit from using high-flux membranes. Nat Rev Nephrol 5, 434–436 (2009). https://doi.org/10.1038/nrneph.2009.95

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