Research has highlighted the importance of the stroma in pancreatic cancer, in particular the role of complex interactions between cancer and stromal cells. A new study describes a novel mechanism by which stromal pathways can be modulated to inhibit tumour growth. The findings support the concept that a multipronged therapeutic approach targeting pancreatic cancer cells and cancer stroma could improve clinical outcomes for this disease.
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Acknowledgements
The authors acknowledge the support of grant funding from the National Health and Medical Research Council of Australia and the New South Wales Cancer Council.
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Apte, M., Wilson, J. A multipronged approach to pancreatic cancer treatment. Nat Rev Gastroenterol Hepatol 13, 385–387 (2016). https://doi.org/10.1038/nrgastro.2016.75
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DOI: https://doi.org/10.1038/nrgastro.2016.75
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