A recent study demonstrates that concurrent flexible sigmoidoscopy in conjunction with CT colonography (CTC) does not improve the diagnostic yield for left-sided colorectal neoplasia compared with CTC alone. This study provides further evidence that CTC is not only more sensitive than the double contrast barium enema, but could be superior to endoscopy for initial evaluation.
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References
Selinger, C. P. et al. Flexible sigmoidoscopy does not significantly increase polyp and cancer detection yield when used to supplement CT colonography. Digestion 85, 55–60 (2012).
Baxter, N. N. et al. Association of colonoscopy and death from colorectal cancer. Ann. Intern. Med. 150, 1–8 (2009).
Pickhardt, P. J., Kim, D. H. & Hassan, C. The effectiveness of colonoscopy in reducing mortality from colorectal cancer. Ann. Intern. Med. 150, 818–819 (2009).
Kim, D. H. et al. CT colonography versus colonoscopy for the detection of advanced neoplasia. N. Engl. J. Med. 357, 1403–1412 (2007).
Pickhardt, P. J. et al. Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N. Engl. J. Med. 349, 2191–2200 (2003).
Pickhardt, P. J., Hassan, C., Halligan, S. & Marmo, R. Colorectal cancer: CT colonography and colonoscopy for detection--systematic review and meta-analysis. Radiology 259, 393–405 (2011).
Atkin, W. S. et al. Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial. Lancet 375, 1624–1633 (2010).
Levin, B. et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. CA Cancer J. Clin. 58, 130–160 (2008).
Pickhardt, P. J., Durick, N. A., Pooler, B. D. & Hassan, C. Left-sided polyps detected at screening CT colonography: do we need complete optical colonoscopy for further evaluation? Radiology 259, 429–434 (2011).
Sweet, A. et al. The impact of CT colonography for colorectal cancer screening on the UK NHS: costs, healthcare resources and health outcomes. Appl. Health Econ. Health Policy 9, 51–64 (2011).
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The author has been a consultant for Bracco, Medicsight, Viatronix and VirtuoCTC.
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Pickhardt, P. Diagnostic yield of flexible sigmoidoscopy and CTC. Nat Rev Gastroenterol Hepatol 9, 195–196 (2012). https://doi.org/10.1038/nrgastro.2012.40
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DOI: https://doi.org/10.1038/nrgastro.2012.40
