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Adrenal disease

Imitating the cortisol profile improves the immune system

Nature Reviews Endocrinology volume 14, pages 137–139 (2018)Cite this article

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A once-daily, modified-release hydrocortisone medication reduces BMI and improves glucose metabolism compared with the twice- or thrice-daily standard hydrocortisone treatment in patients with adrenal insufficiency. Now, further evidence emerges that changing to a once-daily, modified-release hydrocortisone medication improves the immune cell profile and results in fewer infections.

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Authors and Affiliations

  1. Endocrinology in Charlottenburg, Stuttgarter Platz 1, Berlin, 10627, Germany

    Lisa Müller & Marcus Quinkler

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  1. Lisa Müller
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  2. Marcus Quinkler
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Correspondence to Marcus Quinkler.

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Competing interests

M.Q. received honoraria for talks and consultancy from Viropharma/Shire.

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Müller, L., Quinkler, M. Imitating the cortisol profile improves the immune system. Nat Rev Endocrinol 14, 137–139 (2018). https://doi.org/10.1038/nrendo.2018.5

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