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Obesity

Slim without the gym — the magic of chilling out

Nature Reviews Endocrinology volume 12, pages 252–254 (2016)Cite this article

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Cold exposure enhances brown adipose tissue activity, the beiging of white adipose tissue and might have antidiabetic and antiobesity effects. In new data, cold exposure induces and sustains brown adipose tissue in metabolically healthy individuals with obesity, suggesting that cold treatment might be clinically beneficial, even for those with increased BMI.

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Figure 1: Cold-induced changes in BAT activity in healthy individuals with obesity.

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Acknowledgements

P.E.S. is supported by NIH grants R01-DK55758, R01-DK099110 and P01-DK088761 (P.E.S.) and Cancer Prevention Research Institute of Texas grant RP140412. We would like to thank our colleague O. Oz for help with Fig. 1.

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Authors and Affiliations

  1. Department of Radiation Oncology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, 75390–8549, Texas, USA

    Puneeth Iyengar

  2. Department of Internal Medicine and Department of Cell Biology, Touchstone Diabetes Center, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, 75390–8549, Texas, USA

    Philipp E. Scherer

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  1. Puneeth Iyengar
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  2. Philipp E. Scherer
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Correspondence to Philipp E. Scherer.

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Iyengar, P., Scherer, P. Slim without the gym — the magic of chilling out. Nat Rev Endocrinol 12, 252–254 (2016). https://doi.org/10.1038/nrendo.2016.20

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