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Decade in review—type 2 diabetes mellitus

At the centre of things

Over the past decade, the growing epidemic of type 2 diabetes mellitus (T2DM) and its associated complications has presented both challenges and opportunities. Progress has been made in incretin-based therapies, bariatric surgeries and inhibiting renal glucose reabsorption; however, long-term safety and efficacy studies are required. Advances in the prevention of macrovascular complications of T2DM from ongoing clinical trials are expected soon.

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Acknowledgements

The author's work is supported by the National Basic Research Program of China (2015CB553601), the National Science and Technology Pillar Program of China (2013BAI09B13) and by grants from the National Natural Science Foundation of China (grant numbers 81390350, 81321001 and 81261120564).

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Correspondence to Guang Ning.

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Ning, G. At the centre of things. Nat Rev Endocrinol 11, 636–638 (2015). https://doi.org/10.1038/nrendo.2015.147

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