Defining follicular thyroid lesions with indeterminate cytology as either benign or malignant without surgery is an important clinical challenge. Maia and colleagues integrated the Thyroid Imaging and Data Reporting System with the Bethesda System for malignancy risk classification; their report suggests that this method leads to increased diagnostic accuracy with direct clinical implications.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Cibas, E. S., Ali, S. Z. & NCI Thyroid FNA State of the Science Conference. The Bethesda System for reporting thyroid cytopathology. Am. J. Clin. Pathol. 132, 658–665 (2009).
Theoharis, C., Roman, S. & Sosa, J. A. The molecular diagnosis and management of thyroid neoplasms. Curr. Opin. Oncol. 24, 35–41 (2012).
Park, J. Y. et al. A proposal for a thyroid imaging reporting and data system for ultrasound features of thyroid carcinoma. Thyroid 19, 1257–1264 (2009).
Maia, F. R., Matos, P. S., Pavin, E. J. & Zantut-Wittmann, D. E. Thyroid Imaging Reporting and Data System score combined with Bethesda System for malignancy risk stratification in thyroid nodules with indeterminate results on cytology. Clin. Endocrinol. (Oxf.) http://dx.doi.org/10.1111/cen.12525.
Russ, G. et al. Prospective evaluation of thyroid imaging reporting and data system on 4,550 nodules with and without elastography. Eur. J. Endocrinol. 168, 649–655 (2013).
Kwak, J. Y. et al. Thyroid imaging reporting and data system for US features of nodules: a step in establishing better stratification of cancer risk. Radiology 260, 892–899 (2011).
Horvath, E. et al. An ultrasonogram reporting system for thyroid nodules stratifying cancer risk for clinical management. J. Clin. Endocrinol. Metab. 94, 1748–1751 (2009).
Gweon, H. M., Son, E. J., Youk, J. H. & Kim, J. A. Thyroid nodules with Bethesda System III cytology: can ultrasonography guide the next step? Ann. Surg. Oncol. 20, 3083–3088 (2013).
Ho, A. S. et al. Malignancy rate in thyroid nodules classified as Bethesda category III (AUS/FLUS). Thyroid http://dx.doi.org/10.1089/thy.2013.0317.
Bukhari, M. H., Sindi, K. A., Niazi, S., Arshad, M. & Akhtar, Z M. Better thyroid cytopathology reporting system may increase the clinical management and patients outcome: with review of literature. J. Cytol. Histol. 3, 158 (2012).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Maffione, A., Rubello, D. Indeterminate thyroid nodules—two scores are better than one. Nat Rev Endocrinol 10, 580–581 (2014). https://doi.org/10.1038/nrendo.2014.140
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrendo.2014.140
