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Biomarkers of cardiovascular outcomes—bonanza or bias?

During the past decade, a plethora of biomarkers have been reported to be associated with incident cardiovascular disease, often in large meta-analyses. A new review of these meta-analyses suggests that many of these studies are subject to substantial bias; therefore, how should we interpret the results, and where do we go from here?

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Correspondence to Connie W. Tsao.

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The authors declare no competing financial interests.

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Tsao, C., Vasan, R. Biomarkers of cardiovascular outcomes—bonanza or bias?. Nat Rev Endocrinol 9, 381–382 (2013). https://doi.org/10.1038/nrendo.2013.99

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