A recent observational study has reported that androgen deprivation therapy for prostate cancer is associated with an increased risk of acute kidney injury. As a result of limited biological plausibility and critical measured and unmeasured confounders, the reported link is more likely to be casual than causal.
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Smith, M. ADT and acute kidney injury—causal or casual relationship?. Nat Rev Endocrinol 9, 568–570 (2013). https://doi.org/10.1038/nrendo.2013.167
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DOI: https://doi.org/10.1038/nrendo.2013.167