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Risks of hemodynamic instability in pheochromocytoma

Surgical resection of pheochromocytoma is associated with a high risk of intraoperative hemodynamic instability owing to abrupt changes in tumoral catecholamine secretion. A study by Bruynzeel et al. has now assessed preoperative risk factors and the efficacy of presurgical treatment with two different α-adrenergic receptor antagonists.

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Figure 1: Considerations for good clinical practice in the preoperative medical management of patients with pheochromocytoma.

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Correspondence to Graeme Eisenhofer.

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Eisenhofer, G., Bornstein, S. Risks of hemodynamic instability in pheochromocytoma. Nat Rev Endocrinol 6, 301–302 (2010). https://doi.org/10.1038/nrendo.2010.65

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