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Diabetes

Treatment of diabetes mellitus: new tricks by an old player

Nature Reviews Endocrinology volume 6, pages 482–483 (2010)Cite this article

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Case reports published over 100 years ago suggested that high-dose sodium salicylate could reduce the symptoms of type 2 diabetes mellitus, but adverse affects precluded clinical use. Now, results from the TINSAL-T2D study that used salsalate, a salicylate prodrug, provide renewed hope for NSAID treatment of type 2 diabetes mellitus.

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Authors and Affiliations

  1. The Centre of Inflammation and Metabolism at the Department of Infectious Diseases, and Copenhagen Muscle Research Centre, Rigshospitalet, the Faculty of Health Sciences, University of Copenhagen, Section 7641, Blegdamsvej 9, Copenhagen, DK-2100, Denmark

    Bente K. Pedersen

  2. Cellular and Molecular Metabolism Laboratory, Baker IDI Heart & Diabetes Institute, 75 Commercial Road, Melbourne, 3004, Vic, Australia

    Mark A. Febbraio

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  1. Bente K. Pedersen
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  2. Mark A. Febbraio
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Correspondence to Bente K. Pedersen.

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The authors declare no competing financial interests.

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Pedersen, B., Febbraio, M. Treatment of diabetes mellitus: new tricks by an old player. Nat Rev Endocrinol 6, 482–483 (2010). https://doi.org/10.1038/nrendo.2010.130

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