CRISPR-based medicines are racing towards the clinic, barely a blink of an eye since scientists reported in 2013 that the gene-editing tool could be used to cut DNA in human cells. Biotech firms including Editas Medicine, CRISPR Therapeutics and Intellia Therapeutics are all ramping up for first-in-human trials, likely to start next year. For Katrine Bosley, CEO of Editas and fast-car aficionado, this breakneck development trajectory has made for an exciting ride. She spoke with Asher Mullard about the technological tractability of CRISPR, the future of the modality and the importance of engaging in ethical debates about the use of the gene-editing technology.
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Katrine Bosley. Nat Rev Drug Discov 16, 672–673 (2017). https://doi.org/10.1038/nrd.2017.191
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DOI: https://doi.org/10.1038/nrd.2017.191