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Lung cancer

Stage III NSCLC — is it time to centralize care?

Nature Reviews Clinical Oncology volume 13, pages 657–658 (2016)Cite this article

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Eaton et al. report a very strong association between institutional clinical trial accrual volume and the survival of patients with stage III NSCLC. The observed volume effect might have been exaggerated by artefact. More work is required to quantify the volume effect and understand its causes, before rushing to centralize care.

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Authors and Affiliations

  1. William J. Mackillop is at the Division of Cancer Care and Epidemiology, and the Departments of Public Health Sciences, Queen's Cancer Research Institute, and Oncology, Queen's University, 10 Stuart Street, Kingston, Ontario K7L 3N6, Canada.,

    William J. Mackillop

  2. Christopher M. Booth is at the Division of Cancer Care and Epidemiology, and the Departments of Public Health Sciences, Queen's Cancer Research Institute, Oncology, and Medicine, Queen's University, 10 Stuart Street, Kingston, Ontario K7L 3N6, Canada.,

    Christopher M. Booth

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  1. William J. Mackillop
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  2. Christopher M. Booth
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Correspondence to William J. Mackillop.

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The authors declare no competing financial interests.

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Mackillop, W., Booth, C. Stage III NSCLC — is it time to centralize care?. Nat Rev Clin Oncol 13, 657–658 (2016). https://doi.org/10.1038/nrclinonc.2016.160

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