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  • Year in Review
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Lung cancer in 2015

Bypassing checkpoints, overcoming resistance, and honing in on new targets

Lung-cancer treatment paradigms continue to advance as we exploit our growing understanding of the genetic basis of both tumorigenesis and therapy resistance. Moreover, ongoing developments with targeted therapies are improving patient outcomes, with two new drugs approved in 2015 for non-small-cell lung cancer and many others showing promise.

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Correspondence to Egbert F. Smit.

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Smit, E., Baas, P. Bypassing checkpoints, overcoming resistance, and honing in on new targets. Nat Rev Clin Oncol 13, 75–76 (2016). https://doi.org/10.1038/nrclinonc.2015.223

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