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Prostate cancer

A new look at prostate cancer treatment complications

A recent population-based analysis from Nam and coauthors found high complication rates occurring within 5 years of prostatectomy or radiation therapy interventions for prostate cancer. These findings emphasize that treatments should be reserved for men at significant risk of disease progression, and perhaps further concentrated into higher-volume centres of excellence.

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References

  1. Nam, R. K., et al. Incidence of complications other than urinary incontinence or erectile dysfunction after radical prostatectomy or radiotherapy for prostate cancer: a population-based cohort study. Lancet Oncol. 15, 223–231 (2014).

    Article  Google Scholar 

  2. Sonn, G. et al. Differing perceptions of quality of life in patients with prostate cancer and their doctors. J. Urol. 182, 2296–2302 (2009).

    Article  Google Scholar 

  3. Begg, C. et al. Variations in morbidity after radical prostatectomy. N. Engl. J. Med. 346, 1138–1144 (2002).

    Article  Google Scholar 

  4. Pace, K. T., Provan, J. L. & Jewett, M. A. The urology work force in Ontario for the 21st century: feast or famine? Can. J. Surg. 42, 181–189 (1999).

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Savage, C. J. & Vickers, A. J. Low annual caseloads of United States surgeons conducting radical prostatectomy. J. Urol. 182, 2677–2679 (2009).

    Article  Google Scholar 

  6. Chen, A. B., D'Amico, A. V., Neville, B. A., Steyerberg, E. W. & Earle, C. C. Provider case volume and outcomes following prostate brachytherapy. J. Urol. 181, 113–118 (2009).

    Article  Google Scholar 

  7. Tewari, A. et al. Positive surgical margin and perioperative complication rates of primary surgical treatments for prostate cancer: a systematic review and meta-analysis comparing retropubic, laparoscopic, and robotic prostatectomy. Eur. Urol. 62, 1–15 (2012).

    Article  Google Scholar 

  8. Cooperberg, M. R., Odisho, A. Y. & Carroll, P. R. Outcomes for radical prostatectomy: is it the singer, the song, or both? J. Clin. Oncol. 30, 476–478 (2012).

    Article  Google Scholar 

  9. Cooperberg, M. R., Vickers, A. J., Broering, J. M. & Carroll, P. R. Comparative risk-adjusted mortality outcomes after primary surgery, radiotherapy, or androgen-deprivation therapy for localized prostate cancer. Cancer 116, 5226–5234 (2010).

    Article  Google Scholar 

  10. Ganz, P. A. et al. National Institutes of Health State-of-the-Science Conference: role of active surveillance in the management of men with localized prostate cancer. 156, 591–595 (2012).

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Correspondence to Matthew R. Cooperberg.

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Cooperberg, M. A new look at prostate cancer treatment complications. Nat Rev Clin Oncol 11, 304–305 (2014). https://doi.org/10.1038/nrclinonc.2014.58

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