A number of recent observational studies have shown that statins might be associated with a lower risk of gastric cancer. This finding is now supported by a systematic review and meta-analysis. The authors included 11 studies, covering a total of 5,581 cases of gastric cancer and showed a 32% reduction in gastric cancer risk was associated with statin use. After excluding one study that was contributing to considerable heterogeneity in their results, a significant 16% reduction was defined as a more-consistent estimate of the reduction in gastric cancer risk associated with statin use. This chemopreventative association was present in both Asian and Western populations and was dose dependent.
ORIGINAL RESEARCH PAPER
Singh, P. P. & Singh, S. Statins are associated with reduced risk of gastric cancer: a systematic review and meta-analysis. Ann. Oncol. doi:10.1093/annonc/mdt150
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Reduced risk of gastric cancer associated with statins. Nat Rev Clin Oncol 10, 304 (2013). https://doi.org/10.1038/nrclinonc.2013.76
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DOI: https://doi.org/10.1038/nrclinonc.2013.76