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Head and neck cancer in 2010

Maximizing survival and minimizing toxicity

Outcomes for patients with oropharyngeal cancer are determined by their tumor characteristics and associated demographics. The role of human papilloma virus-related disease for prognosis and outcomes with chemoradiotherapy is being more clearly defined. EGFR inhibitors are used in conjunction with radiotherapy, and the importance of optimizing radiation quality and minimizing toxicity is the focus of ongoing studies.

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Correspondence to Bruce E. Brockstein.

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Competing interests

B. E. Brockstein has worked as a consultant for Exelixis, Novartis, and Oncolytics, and is on the speakers bureau (honoraria) for Novartis. E. E. Vokes has worked as a consultant for Bristol-Myers Squibb, Eli Lilly, and ImClone.

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Brockstein, B., Vokes, E. Maximizing survival and minimizing toxicity. Nat Rev Clin Oncol 8, 72–74 (2011). https://doi.org/10.1038/nrclinonc.2010.226

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