One of the seven ongoing trials of accelerated partial breast irradiation (APBI) has concluded that single-dose intraoperative radiotherapy should be considered as an alternative to protracted whole-breast irradiation. With a median follow up of 2 years, such conclusions seem premature. Until the risk and pattern of breast recurrence is reported at longer follow up, TARGIT APBI should remain an experimental approach.
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Sarin, R. Ultra-targeted APBI using TARGIT—a cautionary note. Nat Rev Clin Oncol 7, 675–676 (2010). https://doi.org/10.1038/nrclinonc.2010.187
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DOI: https://doi.org/10.1038/nrclinonc.2010.187