The true prognostic implication of carotid intima–media thickness (CIMT) remains a major question for clinicians and the preventive cardiology community. The merits of using CIMT for assessing asymptomatic individuals at risk for developing cardiovascular disease are discussed, together with the potential issues arising from an analysis of CIMT measurement in the Framingham Offspring Study cohort.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Polak, J. F. et al. Carotid-wall intima–media thickness and cardiovascular events. N. Engl. J. Med. 365, 213–221 (2011).
Greenland, P. et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J. Am. Coll. Cardiol. 5 6, e50–e103 (2010).
Nambi, V. et al. Carotid intima–media thickness and presence or absence of plaque improves prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study. J. Am. Coll. Cardiol. 55, 1600–1607 (2010).
Folsom, A. R. et al. Coronary artery calcification compared with carotid intima–media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA). Arch. Intern. Med. 168, 1333–1339 (2008).
Stein, J. H. et al. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima–Media Thickness Task Force. J. Am. Soc. Echocardiogr. 21, 93–111 (2008).
Society of Atherosclerosis Imaging and Prevention Developed in collaboration with the International Atherosclerosis Society. Appropriate use criteria for carotid intima–media thickness testing. Atherosclerosis 214, 43–46 (2011).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Budoff, M. Should we use CIMT testing? New insights from Framingham. Nat Rev Cardiol 8, 615–616 (2011). https://doi.org/10.1038/nrcardio.2011.144
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrcardio.2011.144
This article is cited by
-
The Role of Carotid Intimal Thickness Testing and Risk Prediction in the Development of Coronary Atherosclerosis
Current Atherosclerosis Reports (2013)