Drug-eluting stents are an established treatment option for coronary artery disease, although they are not without their problems. The MAHOROBA® stent attempts to harness the theoretical advantages of both tacrolimus and polymer degradation, but has proved not to be effective in the treatment of de novo coronary lesions.
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Holmes, D. A new drug-eluting stent that does not live up to its promise. Nat Rev Cardiol 6, 500–501 (2009). https://doi.org/10.1038/nrcardio.2009.117
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DOI: https://doi.org/10.1038/nrcardio.2009.117