Abstract
D-Lysine has been genetically introduced into diketoreductase in E. coli cells by utilization of an orthogonal Ph tRNA /Lysyl-tRNA synthetase pair. This is the first report on the genetic incoporation of D-amino acids into proteins, which may be generally applicable to a wide variety of applications.
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Liu, Z., Yang, X., Yi, D. et al. Genetic incorporation of D-Lysine into diketoreductase in Escherichia coli cells. Nat Prec (2012). https://doi.org/10.1038/npre.2012.6777.1
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DOI: https://doi.org/10.1038/npre.2012.6777.1