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Genome editing: The efficient tool CRISPR–Cpf1

The novel features of the CRISPR–Cpf1 RNA-guided endonuclease system facilitate precise and efficient genome engineering. Application of CRISPR–Cpf1 in plants shows promise for robust gene editing and regulation, opening exciting possibilities for targeted trait improvement in crops.

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Figure 1: Plant genome engineering and targeted gene repression with the CRISPR–Cpf1 system.

References

  1. Pennisi, E. Science 327, 802–803 (2010).

    Article  CAS  Google Scholar 

  2. Eid, A. & Mahfouz, M. M. Exp. Mol. Med. 48, e265 (2016).

    Article  CAS  Google Scholar 

  3. Aouida, M. et al. PLoS ONE 10, e0133373 (2015).

    Article  Google Scholar 

  4. Zetsche, B. et al. Cell 163, 759–771 (2015).

    Article  CAS  Google Scholar 

  5. Ali, Z. et al. Mol. Plant 8, 1288–1291 (2015).

    Article  CAS  Google Scholar 

  6. Tang, X. et al. Nat. Plants 3, 17018 (2017).

    Article  CAS  Google Scholar 

  7. Endo, A., Masafumi, M., Kaya, H. & Toki, S. Sci. Rep. 6, 38169 (2016).

    Article  CAS  Google Scholar 

  8. Xu, R. et al. Plant Biotechnol. J. http://doi.org/bzh2 (2016).

    Google Scholar 

  9. Fu, Y. et al. Nat. Biotechnol. 31, 822–826 (2013).

    Article  CAS  Google Scholar 

  10. Piatek, A. et al. Plant Biotechnol. J. 13, 578–589 (2015).

    Article  CAS  Google Scholar 

Download references

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Correspondence to Magdy M. Mahfouz.

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Mahfouz, M. Genome editing: The efficient tool CRISPR–Cpf1. Nature Plants 3, 17028 (2017). https://doi.org/10.1038/nplants.2017.28

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