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Epigenetics: A tug of war for DNA methylation

A new study uncovers thousands of RNA-directed DNA methylation target sites masked by the active removal of methylated cytosines by a demethylating enzyme.

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Figure 1: Homeostasis of DNA methylation in Arabidopsis is a result of antagonistic DNA methylation and demethylation.

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Correspondence to Tzung-Fu Hsieh.

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Hsieh, TF. Epigenetics: A tug of war for DNA methylation. Nature Plants 2, 16171 (2016). https://doi.org/10.1038/nplants.2016.171

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