Brief Communication

The wheat Sr50 gene reveals rich diversity at a cereal disease resistance locus

  • Nature Plants 1, Article number: 15186 (2015)
  • doi:10.1038/nplants.2015.186
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Abstract

We identify the wheat stem rust resistance gene Sr50 (using physical mapping, mutation and complementation) as homologous to barley Mla, encoding a coiled-coil nucleotide-binding leucine-rich repeat (CC-NB-LRR) protein. We show that Sr50 confers a unique resistance specificity different from Sr31 and other genes on rye chromosome 1RS, and is effective against the broadly virulent Ug99 race lineage. Extensive haplotype diversity at the rye Sr50 locus holds promise for mining effective resistance genes.

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Acknowledgements

This work was supported by funds provided through Grains Research and Development Corporation (CSP00161 and US00063). H.Š. and J.D. are supported by the National Program of Sustainability I (award LO1204). We are grateful to T. Richardson, D. Bhatt, S. Louis, X. Xia (CSIRO Agriculture, Australia) H. Miah and S. Hoxha (The University of Sydney, Australia) for technical assistance.

Author information

Affiliations

  1. CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia

    • Rohit Mago
    • , Sambasivam Periyannan
    • , Michael A. Ayliffe
    • , Wolfgang Spielmeyer
    • , Evans S. Lagudah
    • , Jeff G. Ellis
    •  & Peter N. Dodds
  2. Plant Breeding Institute, The University of Sydney, Private Bag 4011, Narellan, New South Wales 2567, Australia

    • Peng Zhang
    • , Urmil Bansal
    • , Haydar Karaoglu
    • , Harbans Bariana
    • , Robert F. Park
    •  & Robert McIntosh
  3. INRA – CNRGV, 24 Chemin de Borde Rouge – Auzeville, CS 52627, Castanet Tolosan Cedex 31326, France

    • Sonia Vautrin
    •  & Hélène Bergès
  4. Institute of Experimental Botany, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelů 31, Olomouc CZ-78371, Czech Republic

    • Hana Šimková
    •  & Jaroslav Doležel
  5. Department of Plant Sciences, University of California, Davis, California 95616, USA

    • Ming-Cheng Luo
  6. USDA, ARS Cereal Disease Laboratory, University of Minnesota, Saint Paul, Minnesota 55108, USA

    • Matthew Rouse
    • , James Kolmer
    •  & Yue Jin

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Contributions

R.M., J.E., P.D. and E.L. conceived and planned the work. R.M., P.Z., S.V., H.S., U.B., M.-C.L., M.R., H.K., S.P., J.K., Y.J., M.A., H.S.B., R.F.P., R.McI., J.D. and H.B. performed the experiments and analysed the data. R.M. and P.D. wrote the manuscript and all co-authors commented on the draft.

Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Peter N. Dodds.

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