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Gene delivery

Designer DNA give RNAi more spine

Precisely engineered DNA nanostructures can be used to deliver small interfering RNA molecules into cells and tumours to suppress genes.

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Figure 1: Targeting DNA tetrahedra to a tumour in a mouse model.

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Correspondence to Yamuna Krishnan.

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Bhatia, D., Chakraborty, S. & Krishnan, Y. Designer DNA give RNAi more spine. Nature Nanotech 7, 344–346 (2012). https://doi.org/10.1038/nnano.2012.87

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