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An animal model of vascular amyloidosis

A new study presents the first mouse model of hereditary cerebral hemorrhage with amyloidosis–Dutch type, a disease associated with amyloid deposits in the brain's vasculature, and gives insights into Aβ deposition that may be relevant to Alzheimer disease treatment.

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Figure 1: APP pathogenic mutations.

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Ghiso, J., Wisniewski, T. An animal model of vascular amyloidosis. Nat Neurosci 7, 902–904 (2004). https://doi.org/10.1038/nn0904-902

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