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Should I stay or should I go: genetic bases for uncertainty-driven exploration

In the face of uncertainty, how do we choose between maintaining our current strategy or trying new strategies? A study shows that a gene controlling prefrontal dopamine function is predictive of uncertainty-driven exploration.

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Figure 1: The neural substrates of learning from rewards, errors and exploring.

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Sallet, J., Rushworth, M. Should I stay or should I go: genetic bases for uncertainty-driven exploration. Nat Neurosci 12, 963–965 (2009). https://doi.org/10.1038/nn0809-963

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