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Subtracting the Math: prominin-positive cerebellar stem cells in white matter

A study in this issue describes the first multipotent stem cell identified in the postnatal cerebellum. These cells can generate inhibitory interneurons, astrocytes and oligodendrocytes. They may also be responsible for a class of childhood brain tumors.

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Figure 1: Cells of the mature cerebellum have distinctive morphologies and are located in identifiable layers.
Figure 2: Basic FGF–responsive stem cells in the cerebellar white matter generate GABAergic interneurons, astrocytes and oligodendrocytes.

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Kenney, A., Segal, R. Subtracting the Math: prominin-positive cerebellar stem cells in white matter. Nat Neurosci 8, 699–701 (2005). https://doi.org/10.1038/nn0605-699

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