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The need for a cool head: reversible inactivation reveals functional segregation in auditory cortex

'What' and 'where' pathways are recognized in the visual system, but do they exist in auditory cortex? A new study uses reversible inactivation to demonstrate a double dissociation between two cortical regions in two tasks.

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Figure 1: The effects of cooling posterior and anterior regions of auditory cortex are doubly disassociated, with anterior regions being important for discriminating between sounds and posterior parts being important for localizing them.

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Sumner, C., Palmer, A. & Moore, D. The need for a cool head: reversible inactivation reveals functional segregation in auditory cortex. Nat Neurosci 11, 530–531 (2008). https://doi.org/10.1038/nn0508-530

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