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LTP: AMPA receptors trading places

Nature Neuroscience volume 9, pages 593–594 (2006)Cite this article

Many forms of LTP involve insertion of new postsynaptic AMPA receptors. Plant et al. now report transient insertion of Ca2+-permeable AMPA receptors after LTP induction, and find their activation is required for LTP maintenance.

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Figure 1: Changes in the subunit composition of AMPARs during LTP in CA1 pyramidal neurons.

Jessica Iannuzzi

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Authors and Affiliations

  1. Departments of Pharmacology, Physiology and Biotechnology, and Neuroscience, Brown University, Providence, 02912, Rhode Island, USA

    Julie A Kauer

  2. Department of Psychiatry and Behavioral Sciences, Nancy Pritzker Laboratory, Stanford University School of Medicine, 1201 Welch Rd., Room P105, Palo Alto, 94304, California, USA

    Robert C Malenka

Authors
  1. Julie A Kauer
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  2. Robert C Malenka
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Kauer, J., Malenka, R. LTP: AMPA receptors trading places. Nat Neurosci 9, 593–594 (2006). https://doi.org/10.1038/nn0506-593

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