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Axon formation: fate versus growth

Actin destabilization is an early step in specifying axon identity in young neurons. A new paper proposes a molecular mechanism for this process, but the data can also be explained by making a distinction between axon specification and axon growth.

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Figure 1: Models for molecular mechanisms of axon/dendrite specification and axon growth.

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Jiang, H., Rao, Y. Axon formation: fate versus growth. Nat Neurosci 8, 544–546 (2005). https://doi.org/10.1038/nn0505-544

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