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Sodium channels develop a tyrosine phosphatase complex

A new study shows that sodium channels interact with receptor-like tyrosine phosphatase β, which increases sodium currents and may also help localize the channels.

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Figure 1: Regulation of the function of voltage-gated sodium channels by the balance of tyrosine phosphorylation and tyrosine dephosphorylation of the α subunit.

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Salter, M., Tian Wang, Y. Sodium channels develop a tyrosine phosphatase complex. Nat Neurosci 3, 417–419 (2000). https://doi.org/10.1038/74777

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