Motor neurons and muscle fibers interact in complex ways to build the neuromuscular synapse. A new study shows that β-catenin is required in muscle to provide an unknown retrograde signal that is necessary for presynaptic transmitter release.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering
Molecular Brain Open Access 03 December 2008
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Sanes, J.R. & Lichtman, J.W. Nat. Rev. Neurosci. 2, 791–805 (2001).
Fox, M.A. et al. Cell 129, 179–193 (2007).
Li, X.-M. et al. Nat. Neurosci. 11, 262–268 (2008).
Kwiatkowski, A.V., Weis, W.I. & Nelson, W.J. Curr. Opin. Cell Biol. 19, 551–556 (2007).
Togashi, H. et al. Neuron 35, 77–89 (2002).
Salinas, P.C. & Price, S.R. Curr. Opin. Neurobiol. 15, 73–80 (2005).
Zhang, B. et al. J. Neurosci. 27, 3968–3973 (2007).
Ciani, L. & Salinas, P.C. Nat. Rev. Neurosci. 6, 351–362 (2005).
Luo, Z.G. et al. Neuron 35, 489–505 (2002).
Wang, J. et al. Nat. Neurosci. 6, 1017–1018 (2003).
Packard, M. et al. Cell 111, 319–330 (2002).
Tao, H.W. & Poo, M. Proc. Natl. Acad. Sci. USA 98, 11009–11015 (2001).
Fu, A.K. et al. Proc. Natl. Acad. Sci. USA 102, 15224–15229 (2005).
Kim, N. & Burden, S.J. Nat. Neurosci. 11, 19–27 (2008).
Lai, K.O. & Ip, N.Y. Trends Genet. 19, 395–402 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fu, A., Cheung, Z. & Ip, N. β-catenin in reverse action. Nat Neurosci 11, 244–246 (2008). https://doi.org/10.1038/nn0308-244
Issue Date:
DOI: https://doi.org/10.1038/nn0308-244
This article is cited by
-
mRNA expression characteristics are different in irreversibly atrophic intrinsic muscles of the forepaw compared with reversibly atrophic biceps in a rat model of obstetric brachial plexus palsy (OBPP)
Journal of Muscle Research and Cell Motility (2016)
-
alpha-Actinin interacts with rapsyn in agrin-stimulated AChR clustering
Molecular Brain (2008)