ProBDNF has been proposed to alter synaptic plasticity, but whether it is normally released from neurons has been a matter of contention. New work suggests that proBDNF is indeed secreted from central neurons.
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Barker, P. Whither proBDNF?. Nat Neurosci 12, 105–106 (2009). https://doi.org/10.1038/nn0209-105
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DOI: https://doi.org/10.1038/nn0209-105
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