Food intake and energy expenditure were thought to be simultaneously controlled by the same group of neurons, but now new evidence shows that they are independently regulated by an anatomically distinct set of melanocortin neurons.
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Xu, A., Barsh, G. MC4R neurons weigh in differently. Nat Neurosci 9, 15–16 (2006). https://doi.org/10.1038/nn0106-15
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DOI: https://doi.org/10.1038/nn0106-15