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Rare genetic variants and schizophrenia

Nature Neuroscience volume 19, pages 525–527 (2016)Cite this article

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A study reports mutations in a histone methyltransferase gene, SETD1A, in schizophrenia patients and demonstrates that tens of thousands of people must be screened to provide robust evidence of a gene's involvement in schizophrenia.

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Figure 1: The path from exome analysis to gene finding in schizophrenia.

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Authors and Affiliations

  1. Jonathan Flint is in the Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, California, USA.,

    Jonathan Flint

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  1. Jonathan Flint
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Correspondence to Jonathan Flint.

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Flint, J. Rare genetic variants and schizophrenia. Nat Neurosci 19, 525–527 (2016). https://doi.org/10.1038/nn.4271

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