Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Gaining on reward prediction errors

Subjects

In this issue of Nature Neuroscience, Eshel et al. characterize the homogeneity with which individual dopamine neurons encode reward prediction error, a teaching signal that is thought to be crucial for associative learning.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Responses of individual dopamine neurons to varying levels of expected and unexpected reward.

References

  1. Schultz, W. & Dickinson, A. Annu. Rev. Neurosci. 23, 473–500 (2000).

    Article  CAS  Google Scholar 

  2. Steinberg, E.E. et al. Nat. Neurosci. 16, 966–973 (2013).

    Article  CAS  Google Scholar 

  3. Chang, C.Y. et al. Nat. Neurosci. 19, 111–116 (2016).

    Article  CAS  Google Scholar 

  4. Lammel, S. et al. Nature 491, 212–217 (2012).

    Article  CAS  Google Scholar 

  5. Roeper, J. Trends Neurosci. 36, 336–342 (2013).

    Article  CAS  Google Scholar 

  6. Lerner, T.N. et al. Cell 162, 635–647 (2015).

    Article  CAS  Google Scholar 

  7. Neuhoff, H., Neu, A., Liss, B. & Roeper, J. J. Neurosci. 22, 1290–1302 (2002).

    Article  CAS  Google Scholar 

  8. Eshel, N., Tian, J., Bukwich, M. & Uchida, N. Nat. Neurosci. 19, 479–486 (2016).

    Article  CAS  Google Scholar 

  9. Lynd-Balta, E. & Haber, S.N. Neuroscience 59, 625–640 (1994).

    Article  CAS  Google Scholar 

  10. Fiorillo, C.D., Yun, S.R. & Song, M.R. J. Neurosci. 33, 4693–4709 (2013).

    Article  CAS  Google Scholar 

  11. Lammel, S., Ion, D.I., Roeper, J. & Malenka, R.C. Neuron 70, 855–862 (2011).

    Article  CAS  Google Scholar 

  12. Matsumoto, M. & Hikosaka, O. Nature 459, 837–841 (2009).

    Article  CAS  Google Scholar 

  13. Brozoski, T.J., Brown, R.M., Rosvold, H.E. & Goldman, P.S. Science 205, 929–932 (1979).

    Article  CAS  Google Scholar 

  14. Stopper, C.M., Tse, M.T.L., Montes, D.R., Wiedman, C.R. & Floresco, S.B. Neuron 84, 177–189 (2014).

    Article  CAS  Google Scholar 

  15. Hamid, A.A. et al. Nat. Neurosci. 19, 117–126 (2016).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ilana B Witten.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Parker, N., Witten, I. Gaining on reward prediction errors. Nat Neurosci 19, 418–419 (2016). https://doi.org/10.1038/nn.4246

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nn.4246

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing