The serotonin 1A receptor expressed on mature granule cells in the dentate gyrus mediates the behavioral, neurogenic and endocrine effects of the antidepressant fluoxetine in the mouse.
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N.J.B. is employed by, and a shareholder in, AstraZeneca.
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Brandon, N., McKay, R. The cellular target of antidepressants. Nat Neurosci 18, 1537–1538 (2015). https://doi.org/10.1038/nn.4144
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DOI: https://doi.org/10.1038/nn.4144