A leading therapeutic molecule for multiple sclerosis, FTY720, is shown to mimic a key component of sphingolipid signaling, resulting in specific manipulation of histone deacetylases and the extinction of memory.
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Matheos, D., Wood, M. Unlocking the constraints on memory formation. Nat Neurosci 17, 895–896 (2014). https://doi.org/10.1038/nn.3748
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DOI: https://doi.org/10.1038/nn.3748