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Breaking news: thinking may be bad for DNA

Nature Neuroscience volume 16, pages 518519 (2013) | Download Citation

A study in this issue suggests that neuronal DNA double-strand breaks can result from natural behaviors. The breaks occur in the circuits that are activated and are enhanced in a model of Alzheimer's disease. The implications of this finding are far-reaching.

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Author information

Affiliations

  1. Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey, USA.

    • Karl Herrup
    • , Jianmin Chen
    •  & Jiali Li
  2. Karl Herrup is also in the Division of Life Science, Hong Kong University of Science and Technology, Kowloon, Hong Kong.

    • Karl Herrup

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Jiali Li.

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DOI

https://doi.org/10.1038/nn.3384

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