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Host response: Sensing microbial sabotage

Several microbes produce proteases that cleave antibodies to evade immune recognition. Humans seem to have a receptor on myeloid cells that detects the presence of cleaved antibodies and activates innate immunity.

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References

  1. 1.

    et al. Pharmacol. Rev. 67, 462–504 (2015).

  2. 2.

    et al. Nature Immunol. 8, 899–901 (2007).

  3. 3.

    Microbiol. Immunol. 40, 685–699 (1996).

  4. 4.

    et al. Nature Microbiol. 1, 16054 (2016).

  5. 5.

    et al. Immunol. Rev. 267, 117–136 (2015).

  6. 6.

    Semin. Immunol. 20, 311–316 (2008).

  7. 7.

    & Nature Rev. Immunol. 13, 133–144 (2013).

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Author information

Affiliations

  1. John Trowsdale is in the Pathology Department, Tennis Court Road, University of Cambridge, Cambridge CB21QP, UK.

    • John Trowsdale

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Correspondence to John Trowsdale.