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Assess drug-resistance phenotypes, not just genotypes

Whole genome sequencing is often used to determine the presence of known antimicrobial resistance genes and identify new resistance mechanisms. However, without phenotypic confirmation of resistance, caution needs to be taken in attributing relevance to any genes hitherto not shown to confer drug resistance.

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Correspondence to Laura J. V. Piddock.

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Piddock, L. Assess drug-resistance phenotypes, not just genotypes. Nat Microbiol 1, 16120 (2016). https://doi.org/10.1038/nmicrobiol.2016.120

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