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BEAMing: single-molecule PCR on microparticles in water-in-oil emulsions

Nature Methods 3, 551–559 (2006) | Download Citation

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Author information

Affiliations

  1. The Howard Hughes Medical Institute, and The Ludwig Center for Cancer Genetics and Therapeutics, The Johns Hopkins Kimmel Cancer Center, 1650 Orleans Street, Baltimore, Maryland 21231, USA.

    • Frank Diehl
    • , Meng Li
    • , Yiping He
    • , Kenneth W Kinzler
    • , Bert Vogelstein
    •  & Devin Dressman

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Competing interests

Under a licensing agreement between EXACT Sciences and The Jonhs Hopkins University, K.W.K. and B.V. are entitled to a share of royalties received by the university on sales of products related to digital PCR. Under a licensing agreement between Agencourt Biosciences Corporation and The Jonhs Hopkins University, D.D., K.W.K. and B.V. are entitled to a share of royalties received by the university on sales of products related to the use of BEAMing for preparing templates for DNA sequencing. The terms of these arrangements are being managed by The Jonhs Hopkins University in accordance with its conflict of interest policies.

Corresponding author

Correspondence to Bert Vogelstein.

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DOI

https://doi.org/10.1038/nmeth898