Abstract
We observed quantized plasmon quenching dips in resonant Rayleigh scattering spectra by plasmon resonance energy transfer (PRET) from a single nanoplasmonic particle to adsorbed biomolecules. This label-free biomolecular absorption nanospectroscopic method has ultrahigh molecular sensitivity.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Bohren, C.F. & Huffman, D.R. Absorption and Scattering of Light by Small Particles 335–336 (Wiley, New York, 1998).
Moskovits, M. Rev. Mod. Phys. 57, 783–826 (1985).
Lombardi, J.R., Birke, R.L., Lu, T.H. & Xu, J. J. Chem. Phys. 84, 4174–4180 (1986).
Nie, S. & Emory, S.R. Science 275, 1102–1106 (1997).
Futamata, M., Maruyama, Y. & Ishikawa, M. J. Phys. Chem. B 108, 13119–13127 (2004).
Das, P. & Metiu, H. J. Phys. Chem. 89, 4680–4687 (1985).
Andrew, P. & Barnes, W.L. Science 306, 1002–1005 (2004).
Boussaad, S., Pean, J. & Tao, N.J. Anal. Chem. 72, 222–226 (2000).
Haes, A.J., Zou, S., Zhao, J., Schatz, G.C. & Van Duyne, R.P. J. Am. Chem. Soc. 128, 10905–10914 (2006).
Wuttke, D.S., Bjerrum, M.J., Winkler, J.R. & Gray, H.B. Science 256, 1007–1009 (1992).
Lange, C. & Hunte, C. Proc. Natl. Acad. Sci. USA 99, 2800–2805 (2002).
Liu, G.L. et al. Nature Nanotechnol. 1, 47–52 (2006).
Rascheke, G. et al. Nano Lett. 3, 935–938 (2003).
Ambjornsson, T., Mukhopadhyay, G., Apell, S.P. & Kall, M. Phys. Rev. B 73, 085412 (2006).
Romero, M.J., van de Lagemaat, J., Mora-Sero, I., Rumbles, G. & Al-Jasslm, M.M. Nano Lett. 6, 2833–2837 (2006).
Acknowledgements
This work was supported by a grant (05K1501-02810) from 'Center for Nanostructured Materials Technology' under '21st Century Frontier R&D Programs' of the Ministry of Science and Technology, Korea.
Author information
Authors and Affiliations
Contributions
G.L.L. discovered the new finding, conceived the idea and performed the measurements, Y.-T.L. conceived the idea, initiated the experiment, performed the measurements and processed the data, Y.C. repeated the experiments and designed additional experiments, T.K. improved the conjugation chemistry and repeated the experiments, and L.P.L. conceived the idea, designed the experiments and advised other authors.
Corresponding author
Supplementary information
Supplementary Text and Figures
Supplementary Figures 1–4, Supplementary Methods (PDF 1176 kb)
Rights and permissions
About this article
Cite this article
Liu, G., Long, YT., Choi, Y. et al. Quantized plasmon quenching dips nanospectroscopy via plasmon resonance energy transfer. Nat Methods 4, 1015–1017 (2007). https://doi.org/10.1038/nmeth1133
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth1133
This article is cited by
-
Dynamic monitoring of oscillatory enzyme activity of individual live bacteria via nanoplasmonic optical antennas
Nature Photonics (2023)
-
Ultrasensitive and real-time optical detection of cellular oxidative stress using graphene-covered tunable plasmonic interfaces
Nano Convergence (2022)
-
Plasmonic gold nanostructures for biosensing and bioimaging
Microchimica Acta (2021)
-
Investigation on how spectral overlap between donor–acceptor affects PRET
Applied Physics A (2021)
-
Plasmon–exciton coupling of monolayer MoSe2 with self-organized metallic nanoparticles
Applied Physics A (2020)