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Novel at the library

Rapid and accurate identification of protein phosphorylation sites is achieved by a peptide library screen combining the advantages of chemistry in solution and analysis on solid support.

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Figure 1: Schematic of new peptide library screening method.

References

  1. Hutti, J.E. et al. Nat. Methods 1, 27–29 (2004).

    Article  CAS  Google Scholar 

  2. Kemp, B.E., Bylund, D.B., Huang, T.S. & Krebs, E.G. Proc. Natl. Acad. Sci. USA 72, 3448–3452 (1975).

    Article  CAS  Google Scholar 

  3. Daile, P., Carnegie, P.R. & Young, J.D. Nature 257, 416–418 (1975).

    Article  CAS  Google Scholar 

  4. Songyang, Z. Curr. Biol. 4, 973–982 (1994).

    Article  CAS  Google Scholar 

  5. Wu, J., Ma, Q.N. & Lam, K.S. Biochemistry 33, 14825–14833 (1994).

    Article  CAS  Google Scholar 

  6. Rychlewski, L., Kschischo, M., Dong, L., Schutkowski, M. & Reimer, U. J. Mol. Biol. 336, 307–311 (2004).

    Article  CAS  Google Scholar 

  7. Rodriguez, M., Li, S.S., Harper, J.W. & Songyang, Z. J. Biol. Chem. 279, 8802–8807 (2004).

    Article  CAS  Google Scholar 

  8. Luo, K., Zhou, P. & Lodish, H.F. Proc. Natl. Acad. Sci. USA 92, 11761–11765 (1995).

    Article  CAS  Google Scholar 

  9. Yaffe, M.B. et al. Nat. Biotechnol. 19, 348–353 (2001).

    Article  CAS  Google Scholar 

  10. Bader, G.D. et al. Nucleic Acids Res. 29, 242–245 (2001).

    Article  CAS  Google Scholar 

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Yaffe, M. Novel at the library. Nat Methods 1, 13–14 (2004). https://doi.org/10.1038/nmeth1004-13

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  • DOI: https://doi.org/10.1038/nmeth1004-13

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