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Probing the basis for genotype-phenotype relationships

Transposon mutagenesis coupled with microarray analysis helps to rapidly generate information about changing genotype-phenotype relationships in laboratory-evolved bacteria.

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Figure 1: Methods to determine genotype-phenotype relationships in laboratory-evolved bacteria.

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Cho, BK., Palsson, B. Probing the basis for genotype-phenotype relationships. Nat Methods 6, 565–566 (2009). https://doi.org/10.1038/nmeth0809-565

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