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Human T cell development notched up a level

Nature Methods volume 14, pages 477–478 (2017)Cite this article

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Two complementary approaches for directing human hematopoietic stem cells along the T cell lineage will have applications in both fundamental and translational research.

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Figure 1: Applications and complementarity of the ATO2 (right) and clinical-grade pro-T cell differentiation method3 (left).

References

  1. Brauer, P.M., Singh, J., Xhiku, S. & Zúñiga-Pflücker, J.C. Trends Immunol. 37, 889–901 (2016).

    Article  CAS  Google Scholar 

  2. Seet, C.S. et al. Nat. Methods 14, 521–530 (2017).

    Article  CAS  Google Scholar 

  3. Shukla, S. et al. Nat. Methods 14, 531–538 (2017).

    Article  CAS  Google Scholar 

  4. Payne, K.J. & Crooks, G.M. Immunity 26, 674–677 (2007).

    Article  CAS  Google Scholar 

  5. Taghon, T., Waegemans, E. & Van de Walle, I. Curr. Top. Microbiol. Immunol 360, 75–97 (2012).

    CAS  PubMed  Google Scholar 

  6. Van de Walle, I. et al. J. Exp. Med. 210, 683–697 (2013).

    Article  CAS  Google Scholar 

  7. Radtke, F. et al. Immunity 10, 547–558 (1999).

    Article  CAS  Google Scholar 

  8. Schmitt, T.M. & Zúñiga-Pflücker, J.C. Immunity 17, 749–756 (2002).

    Article  CAS  Google Scholar 

  9. Van de Walle, I. et al. Blood 113, 2988–2998 (2009).

    Article  CAS  Google Scholar 

  10. Gundry, M.C. et al. Cell Rep. 17, 1453–1461 (2016).

    Article  CAS  Google Scholar 

Download references

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Author notes

  1. Anne-Catherine Dolens and Tom Taghon are members of the Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium.

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  1. Tom Taghon

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  1. Anne-Catherine Dolens
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  2. Tom Taghon
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Correspondence to Tom Taghon.

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The authors declare no competing financial interests.

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Dolens, AC., Taghon, T. Human T cell development notched up a level. Nat Methods 14, 477–478 (2017). https://doi.org/10.1038/nmeth.4277

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