Microgel particle precursors bearing peptide substrates for human enzymes crosslink in wound sites to produce bioactive scaffolds in situ that rapidly recruit cells and promote dermal healing.
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References
Ringsdorf, H., Schlarb, B. & Venzmer, J. Angew. Chem. Int. Ed. Engl. 27, 113–158 (1988).
Gale, P. A. & Steed, J. W. (eds) Supramolecular Chemistry: From Molecules to Nanomaterials (Wiley, 2012).
Griffin, D. R., Weaver, W. M., Scumpia, P. O., Di Carlo, D. & Segura, T. Nature Mater. 14, 737–744 (2015).
Ulijn, R. V. J. Mater. Chem. 16, 2217–2225 (2006).
Hu, B.-H. & Messersmith, P. B. J. Am. Chem. Soc. 125, 14298–14299 (2003).
Schense, J. C. & Hubbell, J. A. Bioconj. Chem. 10, 75–81 (1999).
Sakiyama-Elbert, S. E. & Hubbell, J. A. Annu. Rev. Mater. Res. 31, 183–201 (2001).
Patterson, J. & Hubbell, J. A. Biomaterials 31, 7836–7845 (2010).
Lutolf, M. P. Proc. Natl Acad. Sci. USA 100, 5413–5418 (2003).
Burdick, J. A. & Murphy, W. L. Nature Commun. 3, 1269 (2012).
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Grainger, D. Enzymatically crosslinked scaffolds. Nature Mater 14, 662–663 (2015). https://doi.org/10.1038/nmat4337
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DOI: https://doi.org/10.1038/nmat4337
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